Differential behavioral sensitivity to carbon dioxide (CO 2 ) inhalation in rats

Carbon dioxide inhalation causes pulmonary inflammation.

The aim of this study was to assess whether one of the most common poisons of cellular respiration, i.e., carbon dioxide, is proinflammatory. CO(2) is naturally present in the atmosphere at the level of 0.038% and involved in numerous cellular biochemical reactions. We analyzed in vitro the inflammation response induced by exposure to CO(2) for 48 h (0-20% with a constant O(2) concentration of ...

Differential behavioral, physiological, and hormonal sensitivity to LPS challenge in rats

Correspondence: Silvia Bison Neuroscience Centre of Excellence for Drug Discovery, GlaxoSmithKline, Medicines Research Centre, Via A Fleming 4, Verona, Italy Tel +39 045 821 8451 Fax +39 045 821 8375 Email [email protected] Abstract: In animals, systemic administration of lipopolysaccharide (LPS) induces a characteristic set of responses that has been termed sickness behavior. In the prese...

Carbon dioxide sensitivity of zeolitic imidazolate frameworks.

Zeolitic imidazolate frameworks of zinc, cobalt, and cadmium, including the framework ZIF-8 commercially sold as Basolite Z1200, exhibit surprising sensitivity to carbon dioxide under mild conditions. The frameworks chemically react with CO2 in the presence of moisture or liquid water to form carbonates. This effect, which has been previously not reported in metal-organic framework chemistry, p...

Ventilatory responses to rebreathing and carbon dioxide inhalation during anaesthesia in children.

In 12 spontaneously breathing intubated children (9.3-25 kg), ventilatory responses to rebreathing and to the inhalation of carbon dioxide (CO2) were investigated during halothane anaesthesia for minor surgical procedures. A T-piece (Mapleson F system) was used, modified by the insertion of a pneumotachograph and a paediatric airway adaptor of an in-line capnograph in the patient limb. Exhaled ...

[Injuries due to inhalation of sulfur dioxide].